Life sciences and Bio-engineering: Recent submissions
Now showing items 321-340 of 1150
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Participatory mapping identifies risk areas and environmental predictors of endemic anthrax in rural Africa
(Springer Nature Limited, 2022-06-12)Disease mapping reveals geographical variability in incidence, which can help to prioritise control efforts. However, in areas where this is most needed, resources to generate the required data are often lacking. ... -
Multiple Pathogens Contribute to Human Immunodeficiency Virus-Related Sepsis in Addition to Mycobacterium tuberculosis: A Prospective Cohort in Tanzania
(PubMed Central, 2022-10-20)Background: Mortality from tuberculosis (TB) sepsis is common among patients living with human immunodeficiency virus (PLHIV). We aimed to detect M. tuberculosis (MTB) and additional sepsis etiologies, and mortality ... -
Epidemiology of leptospirosis in Tanzania: A review of the current status, serogroup diversity and reservoirs
(PLOS, 2021-11-16)Background Tanzania is among the tropical countries of Sub-Saharan Africa with the environmental conditions favorable for transmission of Leptospira. Leptospirosis is a neglected zoonotic disease, and although there are ... -
Antimicrobial resistant coliforms across four poultry production systems in Arusha and Moshi, Tanzania
(Pan African Medical Journal, 2022-01-11)Introduction: resistance to antimicrobials poses a threat to human and animal health. This study aimed to determine the prevalence of resistant coliforms in poultry cloacal samples collected from different poultry ... -
Taenia multiceps in Northern Tanzania: An Important but Preventable Disease Problem in Pastoral and Agropastoral Farming Systems
(MDPI, 2022-08-26)Coenurosis due to Taenia multiceps has emerged as a major concern to small ruminant-owning communities in northern Tanzania. Although a high incidence of disease has been reported, gaps still remain in our knowledge of the ... -
Kiwira Virus, a Newfound Hantavirus Discovered in Free-Tailed Bats (Molossidae) in East and Central Africa
(MDPI, 2022-10-27)A novel hantavirus, named Kiwira virus, was molecularly detected in six Angolan free- tailed bats (Mops condylurus, family Molossidae) captured in Tanzania and in one free-tailed bat in the Democratic Republic of Congo. ... -
Comparative analysis of clinical breakpoints, normalized resistance interpretation and epidemiological cut-offs in interpreting antimicrobial resistance of Escherichia coli isolates originating from poultry in different farm types in Tanzania
(Microbiology Society, 2014-07-14)Introduction. Existing breakpoint guidelines are not optimal for interpreting antimicrobial resistance (AMR) data from animal studies and low-income countries, and therefore their utility for analysing such data is limited. ... -
Acute and sub-acute toxicity studies of chloroform extracts of cucumis metuliferus and lippia kituiensis in mice and rats model
(World Journal of Pharmaceutical Research, 2020)Objective: To evaluate the acute and sub-acute oral toxicity of Cucumis metuliferus and Lippia kituiensis leaf chloroform extracts in mice and rats model. Methods: Acute oral toxicity study of chloroform extracts of L. ... -
Development of a Natural Product Rich in Bioavailable Omega-3 DHA from Locally Available Ingredients for Prevention of Nutrition Related Mental Illnesses
(Taylor & Francis Online, 2020-03-19)Objectives: Poor mental health remains a serious public concern worldwide. The most vulnerable individuals are children and adolescents in developing countries. Nutritional deficiency of long-chain omega-3 fatty acids, ... -
Solvent effects on host-guest residence time and kinetics: further insights from metadynamics simulation of Toussaintine-A unbiding from chitosan nanoparticle
(Springer Nature, 2021-04-14)Solvents play an important role in host-guest intermolecular interactions. The kinetics and residence time of Toussaintine-A (TouA) unbinding from chitosan was investigated by means of well-tempered metadynamics and ... -
Ensemble-based screening of natural products and FDA-approved drugs identified potent inhibitors of SARS-CoV-2 that work with two distinct mechanisms
(Elsevier Inc., 2021-02-23)The recent outbreak of SARS-CoV-2 is responsible for high morbidity and mortality rate across the globe. This requires an urgent identification of drugs and other interventions to overcome this pandemic. Computational drug ... -
Recent advances in thermochemical conversion of biomass into drop-in fuel:a review
(Elsevier B.V., 2022-09)The global evolutional changes towards the use of renewable energy sources for trans- portation purposes are on the increase in an attempt to mitigate the environmental haz- ard and the proposed depletion associated with ... -
Catalytic hydrothermal liquefaction of orange peels into biocrude: An optimization approach by central composite design
(Elsevier B.V., 2023-08)Global instability, persistent increase in pump-price, inflation and depletion of fossil fuel resources amidst the continuous discharge of greenhouse gases from fossil fuels combustion call for urgent attention. The ... -
Efficiency of a constructed wetland in removing microbial contaminants from pre-treated municipal wastewater
(Elsevier, 2014)In most capital towns, urban wastewater discharging into the environment is highly enriched in a wide range of microbial contaminants, thus threatening people’s health and the quality of the receiving basin water and other ... -
One Health: a concept led by Africa, with global benefits
(BMJ Publishing Group, 2015-05-09)One Health evolved from the recognition that an interdisciplinary approach is required to understand complex health problems, and that the health of humans and animals are inextricably linked. Through closer ... -
Intestinal Schistosomiasis among Primary Schoolchildren in Two On-Shore Communities in Rorya District, Northwestern Tanzania: Prevalence, Intensity of Infection and Associated Risk Factors
(Hindawi, 2016-10-16)In Tanzania, Schistosoma mansoni is of great public health importance. Understanding the prevalence and infection intensity is important for targeted, evidence-based control strategies. This study aimed at studying the ... -
The Efficacy of Single-Dose versus Double-Dose Praziquantel Treatments on Schistosoma mansoni Infections: Its Implication on Undernutrition and Anaemia among Primary Schoolchildren in Two On-Shore Communities, Northwestern Tanzania
(Hindawi, 2017-09-28)Administering more than one treatment may increase Praziquantel cure and egg reduction rates, thereby hastening achievement of schistosomiasis transmission control. A total of 431 S. mansoni-infected schoolchildren were ... -
Multiplex paper-based designs for point-of-care (POC) diagnostics
(International Journal of Research in Medical Sciences, 2018-11)Background: Accurate and timely diagnosis is usually the first step towards appropriate disease management. In resource-limited settings, healthcare workers lack proper facilities to perform vital tests, and the diagnosis ... -
Colorectal Cancer Epidemiology in Tanzania: Patterns in Relation to Dietary and Lifestyle Factors
(American Society of Clinical Oncology, 2018-09-28)Background: Chronic noncommunicable diseases are increasingly captured as contributing to morbidity and mortality in low and middle income countries. Aim: This study aimed to investigate the epidemiology of colorectal ... -
Paraquat-Mediated Oxidative Stress in Anopheles gambiae Mosquitoes Is Regulated by An Endoplasmic Reticulum (ER) Stress Response
(MDPI, 2018-11-12)Paraquat is a potent superoxide (O2−)-inducing agent that is capable of inducing an oxidative imbalance in the mosquito midgut. This oxidative imbalance can super-stress the malaria parasite, leading to arrested development ...
